Origin Harley as a doctor at Arkham Dr. Harleen Quinzel was a psychiatric intern at Arkham Asylum. A model student, in addition to receiving high grades in college, she was also a dedicated gymnast, winning a scholarship to Gotham City University. While researching the lunatics at Arkham, she became fascinated with one particular inmate. Ambitiously volunteering to analyze him, she pleaded with the doctors at Arkham for three months before she could treat him.
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Further information on the setting: Arkham Asylum and Batman: Declaring both the asylum and Blackgate Penitentiary no longer suitable to contain the city's detainees, Sharp's administration orders both facilities closed and he purchases Gotham's most notorious slums, converting them into an immense prison enclosure known as Arkham City. This facility is subsequently placed in the care of psychiatrist Hugo Strange—who is secretly manipulating Sharp—and monitored by a rogue private military firm , TYGER Security. A wary Batman maintains his own vigil over the new project, concerned that the chaotic situation there will get out of hand. Hugo Strange discloses his knowledge of Wayne's dual identity as Batman before releasing him into the prison's criminal populace.
A partir de entonces ha sido un personaje recurrente en las historias de Batman e incluso le fue dada su propia serie. A punto de que se realice esto, ella le dispara al Joker en el hombro. Aunque Sugar escapa, Bruce Wayne se ve impresionado por los esfuerzos de Quinn para redimirse y acepta la libertad condicional de ella. Por lo tanto, abandona a los Seis Secretos. Habiendo renunciado a su disfraz y al maquillaje de payaso, Harley viste una toga.
The Animated Series episode " Joker's Favor ",  as what was originally supposed to be the animated equivalent of a walk-on role; a number of police officers were to be taken hostage by someone jumping out of a pop out cake , and it was decided that to have the Joker do so himself would be too bizarre, although he ended up doing it anyway. Dini thus created a female sidekick for the Joker, who would become his love interest. Arleen Sorkin , a former star of the soap opera Days of Our Lives , appeared in a dream sequence on that series in which she wore a jester costume; Dini used this scene as an inspiration for Quinn. Mad Love recounts the character's origin story.